The Challenges of the Single Micronutrient Study Commentary on Calcium Supplements and Cardiovascular Events

Recently, controversy has arisen based on reports of an increased risk of cardiovascular events associated with calcium supplementation. Publications with the opposing view that calcium supplementation does not increase cardiovascular events have also been recently published, including a meta-analysis and a randomized controlled trial with long term follow-up. This leads to the question of whether calcium supplementation is beneficial for bone but deleterious for the cardiovascular system.